Galantamine-memantine combination effective in dementia: Translate to dementia praecox?

Galantamine-memantine combination effective in dementia: Translate to dementia praecox?

Cholinergic and glutamatergic systems, alpha-7 nicotinic acetylcholine receptor (α-7nAChR) and N-methyl-D-aspartate (NMDA) receptor are strongly implicated with cognitive impairments in Alzheimer's disease (AD). Donepezil, a frequently used drug in the treatment of AD, is only an acetylcholinesterase inhibitor (AChEI), whereas galantamine is an AChEI and a positive allosteric modulator of the α...

Research in Dementia Praecox

This is a book by an American author, Professor N. C. D. Lewis, of Columbia University. It is of a quite unusual kind and is the result of the author's attempt to collect the findings of research work done into the condition during the last fifteen years. Its publication in America was largely made possible by the beneficience of the Scottish Rite Masons. In the prefact it is suggested that it ...

Dementia Praecox. A Psychological Study

The Psychology of Dementia Praecox

The Psychology of Dementia Praecox. By Dr. C. G. Jung. Translated by Frederic^ Peterson, M.D., and A. A. Brill, Ph.B., M.D. Nervous and Mental Disease Monograph Series, No. 3, New York, 1909. Pp. xx + 153. The majority of existing treatises on dementia praecox present, in reality, little more than collections of accurate clinical pictures of the disease. Their aim is to establish a clearer and ...

The Effects of Donepezil, Galantamine, Rivastigmine and Memantine on Mini-Mental State Examination and Mean Flow Velocity in Patients with Vascular Dementia: A Double-Blinded Randomized Clinical Trial

Background: Vascular dementia is one of the most common forms of dementia. At now, there is no treatment available to cure vascular dementia or to alter its clinical course. Some studies suggest that some drugs may be useful in controlling symptoms. The aim of this study was to evaluate the effects of donepezil, memantine, rivastigmine and galantamine on mean flow velocity and ...